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Quetiapine Attenuates Glial Activation and Proinflammatory Cytokines in APP/PS1 Transgenic Mice via Inhibition of Nuclear Factor-κB Pathway

BACKGROUND: In Alzheimer’s disease, growing evidence has shown that uncontrolled glial activation and neuroinflammation may contribute independently to neurodegeneration. Antiinflammatory strategies might provide benefits for this devastating disease. The aims of the present study are to address the...

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Detalles Bibliográficos
Autores principales: Zhu, Shenghua, Shi, Ruoyang, Li, Victor, Wang, Junhui, Zhang, Ruiguo, Tempier, Adrien, He, Jue, Kong, Jiming, Wang, Jun-Feng, Li, Xin-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360237/
https://www.ncbi.nlm.nih.gov/pubmed/25618401
http://dx.doi.org/10.1093/ijnp/pyu022