5-HT(2C) Receptor Desensitization Moderates Anxiety in 5-HTT Deficient Mice: From Behavioral to Cellular Evidence

BACKGROUND: Desensitization and blockade of 5-HT(2C) receptors (5-HT(2C)R) have long been thought to be central in the therapeutic action of antidepressant drugs. However, besides behavioral pharmacology studies, there is little in vivo data documenting antidepressant-induced 5-HT(2C)R desensitizati...

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Detalles Bibliográficos
Autores principales: Martin, Cédric BP, Martin, Vincent S., Trigo, José M., Chevarin, Caroline, Maldonado, Rafael, Fink, Latham H., Cunningham, Kathryn A., Hamon, Michel, Lanfumey, Laurence, Mongeau, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360241/
https://www.ncbi.nlm.nih.gov/pubmed/25522398
http://dx.doi.org/10.1093/ijnp/pyu056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360241/
https://www.ncbi.nlm.nih.gov/pubmed/25522398
http://dx.doi.org/10.1093/ijnp/pyu056

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