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Adjunctive Treatment with Asenapine Augments the Escitalopram-Induced Effects on Monoaminergic Outflow and Glutamatergic Neurotransmission in the Medial Prefrontal Cortex of the Rat

BACKGROUND: Substantial clinical data support the addition of low doses of atypical antipsychotic drugs to selective serotonin reuptake inhibitors (SSRIs) to rapidly enhance the antidepressant effect in treatment-resistant depression. Preclinical studies suggest that this effect is at least partly e...

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Detalles Bibliográficos
Autores principales: Björkholm, Carl, Frånberg, Olivia, Malmerfelt, Anna, Marcus, Monica M., Konradsson-Geuken, Åsa, Schilström, Björn, Jardemark, Kent, Svensson, Torgny H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360248/
https://www.ncbi.nlm.nih.gov/pubmed/25522408
http://dx.doi.org/10.1093/ijnp/pyu068