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Role of elastases in the pathogenesis of chronic obstructive pulmonary disease: Implications for treatment
Neutrophil elastase, metalloproteinases, and their inhibitors play an important role in the development of chronic obstructive pulmonary disease (COPD), resulting in extensive tissue damage and malfunctioning of the airways. Nearly fifty years after the protease-antiprotease imbalance hypothesis has...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360323/ https://www.ncbi.nlm.nih.gov/pubmed/21147616 http://dx.doi.org/10.1186/2047-783X-15-S2-27 |