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Role of elastases in the pathogenesis of chronic obstructive pulmonary disease: Implications for treatment

Neutrophil elastase, metalloproteinases, and their inhibitors play an important role in the development of chronic obstructive pulmonary disease (COPD), resulting in extensive tissue damage and malfunctioning of the airways. Nearly fifty years after the protease-antiprotease imbalance hypothesis has...

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Detalles Bibliográficos
Autores principales: Demkow, U, van Overveld, FJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360323/
https://www.ncbi.nlm.nih.gov/pubmed/21147616
http://dx.doi.org/10.1186/2047-783X-15-S2-27