Ttiotropium increases cytosolic muscarinic M3 receptors and acetylated H3 histone proteins in induced sputum cells of COPD patients

OBJECTIVE: Chronic obstructive pulmonary disease (COPD) is characterized by irreversible progressive airflow limitation related to tobacco smoking. This limitation is caused by chronic inflammation of the airways and lung parenchyma and is associated with increased activity of parasympathetic system...

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Detalles Bibliográficos
Autores principales: Holownia, A, Mroz, RM, Skopinski, T, Kielek, A, Kolodziejczyk, A, Chyczewska, E, Braszko, JJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360339/
https://www.ncbi.nlm.nih.gov/pubmed/21147623
http://dx.doi.org/10.1186/2047-783X-15-S2-64

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360339/
https://www.ncbi.nlm.nih.gov/pubmed/21147623
http://dx.doi.org/10.1186/2047-783X-15-S2-64

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