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Ttiotropium increases cytosolic muscarinic M3 receptors and acetylated H3 histone proteins in induced sputum cells of COPD patients
OBJECTIVE: Chronic obstructive pulmonary disease (COPD) is characterized by irreversible progressive airflow limitation related to tobacco smoking. This limitation is caused by chronic inflammation of the airways and lung parenchyma and is associated with increased activity of parasympathetic system...
Autores principales: | Holownia, A, Mroz, RM, Skopinski, T, Kielek, A, Kolodziejczyk, A, Chyczewska, E, Braszko, JJ |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360339/ https://www.ncbi.nlm.nih.gov/pubmed/21147623 http://dx.doi.org/10.1186/2047-783X-15-S2-64 |
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