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Determination of Base Binding Strength and Base Stacking Interaction of DNA Duplex Using Atomic Force Microscope

As one of the most crucial properties of DNA, the structural stability and the mechanical strength are attracting a great attention. Here, we take advantage of high force resolution and high special resolution of Atom Force Microscope and investigate the mechanical force of DNA duplexes. To evaluate...

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Detalles Bibliográficos
Autores principales: Zhang, Tian-biao, Zhang, Chang-lin, Dong, Zai-li, Guan, Yi-fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360479/
https://www.ncbi.nlm.nih.gov/pubmed/25772017
http://dx.doi.org/10.1038/srep09143