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Enhancer-promoter interaction facilitated by transiently forming G-quadruplexes
G-quadruplexes are guanine-rich nucleic acid sequences capable of forming a four-stranded structure through Hoogsteen hydrogen bonding. G-quadruplexes are highly concentrated near promoters and transcription start sites suggesting a role in gene regulation. They are less often found on the template...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360481/ https://www.ncbi.nlm.nih.gov/pubmed/25772493 http://dx.doi.org/10.1038/srep09165 |