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Enhancer-promoter interaction facilitated by transiently forming G-quadruplexes

G-quadruplexes are guanine-rich nucleic acid sequences capable of forming a four-stranded structure through Hoogsteen hydrogen bonding. G-quadruplexes are highly concentrated near promoters and transcription start sites suggesting a role in gene regulation. They are less often found on the template...

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Detalles Bibliográficos
Autor principal: Hegyi, Hedi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360481/
https://www.ncbi.nlm.nih.gov/pubmed/25772493
http://dx.doi.org/10.1038/srep09165