Multi-species sequence comparison reveals dynamic evolution of the elastin gene that has involved purifying selection and lineage-specific insertions/deletions

BACKGROUND: The elastin gene (ELN) is implicated as a factor in both supravalvular aortic stenosis (SVAS) and Williams Beuren Syndrome (WBS), two diseases involving pronounced complications in mental or physical development. Although the complete spectrum of functional roles of the processed gene pr...

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Detalles Bibliográficos
Autores principales: Piontkivska, Helen, Zhang, Yi, Green, Eric D, Elnitski, Laura
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC436053/
https://www.ncbi.nlm.nih.gov/pubmed/15149554
http://dx.doi.org/10.1186/1471-2164-5-31

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC436053/
https://www.ncbi.nlm.nih.gov/pubmed/15149554
http://dx.doi.org/10.1186/1471-2164-5-31

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