RNA-directed remodeling of the HIV-1 protein Rev orchestrates assembly of the Rev–Rev response element complex

The HIV-1 protein Rev controls a critical step in viral replication by mediating the nuclear export of unspliced and singly-spliced viral mRNAs. Multiple Rev subunits assemble on the Rev Response Element (RRE), a structured region present in these RNAs, and direct their export through the Crm1 pathw...

Descripción completa

Detalles Bibliográficos
Autores principales: Jayaraman, Bhargavi, Crosby, David C, Homer, Christina, Ribeiro, Isabel, Mavor, David, Frankel, Alan D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360532/
https://www.ncbi.nlm.nih.gov/pubmed/25486594
http://dx.doi.org/10.7554/eLife.04120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360532/
https://www.ncbi.nlm.nih.gov/pubmed/25486594
http://dx.doi.org/10.7554/eLife.04120

Ejemplares similares