Use of mitogenic cascade blockers for treatment of C-Raf induced lung adenoma in vivo: CI-1040 strongly reduces growth and improves lung structure

BACKGROUND: Signaling networks promoting cell growth and proliferation are frequently deregulated in cancer. Tumors often are highly dependent on such signaling pathways and may become hypersensitive to downregulation of key components within these signaling cascades. The classical mitogenic cascade...

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Detalles Bibliográficos
Autores principales: Kramer, Boris W, Götz, Rudolf, Rapp, Ulf R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC436059/
https://www.ncbi.nlm.nih.gov/pubmed/15171791
http://dx.doi.org/10.1186/1471-2407-4-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC436059/
https://www.ncbi.nlm.nih.gov/pubmed/15171791
http://dx.doi.org/10.1186/1471-2407-4-24

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