A New Drug Combinatory Effect Prediction Algorithm on the Cancer Cell Based on Gene Expression and Dose–Response Curve

Gene expression data before and after treatment with an individual drug and the IC(20) of dose–response data were utilized to predict two drugs' interaction effects on a diffuse large B-cell lymphoma (DLBCL) cancer cell. A novel drug interaction scoring algorithm was developed to account for ei...

Descripción completa

Detalles Bibliográficos
Autores principales: Goswami, C Pankaj, Cheng, L, Alexander, PS, Singal, A, Li, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360667/
https://www.ncbi.nlm.nih.gov/pubmed/26225234
http://dx.doi.org/10.1002/psp4.9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360667/
https://www.ncbi.nlm.nih.gov/pubmed/26225234
http://dx.doi.org/10.1002/psp4.9

Ejemplares similares