7-Ketocholesterol Increases Retinal Microglial Migration, Activation, and Angiogenicity: A Potential Pathogenic Mechanism Underlying Age-related Macular Degeneration

Age-related macular degeneration (AMD) has been associated with both accumulation of lipid and lipid oxidative products, as well as increased neuroinflammatory changes and microglial activation in the outer retina. However, the relationships between these factors are incompletely understood. 7-Ketoc...

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Detalles Bibliográficos
Autores principales: Indaram, Maanasa, Ma, Wenxin, Zhao, Lian, Fariss, Robert N., Rodriguez, Ignacio R., Wong, Wai T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360733/
https://www.ncbi.nlm.nih.gov/pubmed/25775051
http://dx.doi.org/10.1038/srep09144

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360733/
https://www.ncbi.nlm.nih.gov/pubmed/25775051
http://dx.doi.org/10.1038/srep09144

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