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7-Ketocholesterol Increases Retinal Microglial Migration, Activation, and Angiogenicity: A Potential Pathogenic Mechanism Underlying Age-related Macular Degeneration
Age-related macular degeneration (AMD) has been associated with both accumulation of lipid and lipid oxidative products, as well as increased neuroinflammatory changes and microglial activation in the outer retina. However, the relationships between these factors are incompletely understood. 7-Ketoc...
Autores principales: | Indaram, Maanasa, Ma, Wenxin, Zhao, Lian, Fariss, Robert N., Rodriguez, Ignacio R., Wong, Wai T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360733/ https://www.ncbi.nlm.nih.gov/pubmed/25775051 http://dx.doi.org/10.1038/srep09144 |
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