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Hyperpolarized (15)N-pyridine Derivatives as pH-Sensitive MRI Agents

Highly sensitive MR imaging agents that can accurately and rapidly monitor changes in pH would have diagnostic and prognostic value for many diseases. Here, we report an investigation of hyperpolarized (15)N-pyridine derivatives as ultrasensitive pH-sensitive imaging probes. These molecules are easi...

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Detalles Bibliográficos
Autores principales: Jiang, Weina, Lumata, Lloyd, Chen, Wei, Zhang, Shanrong, Kovacs, Zoltan, Sherry, A. Dean, Khemtong, Chalermchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360734/
https://www.ncbi.nlm.nih.gov/pubmed/25774436
http://dx.doi.org/10.1038/srep09104