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Sumoylation controls the timing of Tup1-mediated transcriptional deactivation

The small ubiquitin-like modifier (SUMO) is implicated in various cellular activities, including transcriptional regulation. We previously showed that the yeast activator Gcn4 becomes sumoylated during activation, facilitating its eventual promoter eviction and transcriptional shut off. Here we show...

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Detalles Bibliográficos
Autores principales: Ng, Chong Han, Akhter, Akhi, Yurko, Nathan, Burgener, Justin M., Rosonina, Emanuel, Manley, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360881/
https://www.ncbi.nlm.nih.gov/pubmed/25766875
http://dx.doi.org/10.1038/ncomms7610