Structures of an intramembrane vitamin K epoxide reductase homolog reveal control mechanisms for electron transfer

The intramembrane vitamin K epoxide reductase (VKOR) supports blood coagulation in humans and is the target of the anticoagulant warfarin. VKOR and its homologs generate disulfide bonds in organisms ranging from bacteria to humans. Here, to better understand the mechanism of VKOR catalysis, we repor...

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Detalles Bibliográficos
Autores principales: Liu, Shixuan, Cheng, Wei, Grider, Ronald Fowle, Shen, Guomin, Li, Weikai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360977/
https://www.ncbi.nlm.nih.gov/pubmed/24477003
http://dx.doi.org/10.1038/ncomms4110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360977/
https://www.ncbi.nlm.nih.gov/pubmed/24477003
http://dx.doi.org/10.1038/ncomms4110

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