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Mesenchymal Stromal Cell Secretome Up-Regulates 47 kDa CXCR4 Expression, and Induce Invasiveness in Neuroblastoma Cell Lines

Neuroblastoma accounts for 15% of childhood cancer deaths and presents with metastatic disease of the bone and the bone marrow at diagnosis in 70% of the cases. Previous studies have shown that the Mesenchymal Stromal Cell (MSC) secretome, triggers metastases in several cancer types such as breast a...

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Detalles Bibliográficos
Autores principales: Shankar, Vipin, Hori, Hiroki, Kihira, Kentaro, Lei, Qi, Toyoda, Hidemi, Iwamoto, Shotaro, Komada, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361348/
https://www.ncbi.nlm.nih.gov/pubmed/25774696
http://dx.doi.org/10.1371/journal.pone.0120069