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CRISPR/Cas9 as Tool for Functional Study of Genes Involved in Preimplantation Embryo Development
The CRISPR/Cas9 system has proven to be an efficient gene-editing tool for genome modification of cells and organisms. However, the applicability and efficiency of this system in pig embryos have not been studied in depth. Here, we aimed to remove porcine OCT4 function as a model case using the CRIS...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361403/ https://www.ncbi.nlm.nih.gov/pubmed/25775469 http://dx.doi.org/10.1371/journal.pone.0120501 |