Cargando…

TFIIB Is Only ∼9 Å Away from the 5'-End of a Trimeric RNA Primer in a Functional RNA Polymerase II Preinitiation Complex

Recent X-ray crystallographic studies of Pol II in complex with the general transcription factor (GTF) IIB have begun to provide insights into the mechanism of transcription initiation. These structures have also shed light on the architecture of the transcription preinitiation complex (PIC). Howeve...

Descripción completa

Detalles Bibliográficos
Autores principales: Bick, Matthew J., Malik, Sohail, Mustaev, Arkady, Darst, Seth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361453/
https://www.ncbi.nlm.nih.gov/pubmed/25774659
http://dx.doi.org/10.1371/journal.pone.0119007