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TFIIB Is Only ∼9 Å Away from the 5'-End of a Trimeric RNA Primer in a Functional RNA Polymerase II Preinitiation Complex
Recent X-ray crystallographic studies of Pol II in complex with the general transcription factor (GTF) IIB have begun to provide insights into the mechanism of transcription initiation. These structures have also shed light on the architecture of the transcription preinitiation complex (PIC). Howeve...
Autores principales: | Bick, Matthew J., Malik, Sohail, Mustaev, Arkady, Darst, Seth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361453/ https://www.ncbi.nlm.nih.gov/pubmed/25774659 http://dx.doi.org/10.1371/journal.pone.0119007 |
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