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A New System for Profiling Drug-Induced Calcium Signal Perturbation in Human Embryonic Stem Cell–Derived Cardiomyocytes

The emergence of human stem cell–derived cardiomyocyte (hSCCM)–based assays in the cardiovascular (CV) drug discovery sphere requires the development of improved systems for interrogating the rich information that these cell models have the potential to yield. We developed a new analytical framework...

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Detalles Bibliográficos
Autores principales: Lewis, Kimberley J., Silvester, Nicole C., Barberini-Jammaers, Steven, Mason, Sammy A., Marsh, Sarah A., Lipka, Magdalena, George, Christopher H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361473/
https://www.ncbi.nlm.nih.gov/pubmed/25367900
http://dx.doi.org/10.1177/1087057114557232