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A New System for Profiling Drug-Induced Calcium Signal Perturbation in Human Embryonic Stem Cell–Derived Cardiomyocytes
The emergence of human stem cell–derived cardiomyocyte (hSCCM)–based assays in the cardiovascular (CV) drug discovery sphere requires the development of improved systems for interrogating the rich information that these cell models have the potential to yield. We developed a new analytical framework...
Autores principales: | Lewis, Kimberley J., Silvester, Nicole C., Barberini-Jammaers, Steven, Mason, Sammy A., Marsh, Sarah A., Lipka, Magdalena, George, Christopher H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361473/ https://www.ncbi.nlm.nih.gov/pubmed/25367900 http://dx.doi.org/10.1177/1087057114557232 |
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