Deficiency of CD8(+) effector memory T cells is an early and persistent feature of multiple sclerosis

BACKGROUND: Patients with multiple sclerosis (MS) have a deficiency of circulating CD8(+) T cells, which might impair control of Epstein–Barr virus (EBV) and predispose to MS by allowing EBV-infected autoreactive B cells to accumulate in the central nervous system. Based on the expression of CD45RA...

Descripción completa

Detalles Bibliográficos
Autores principales: Pender, Michael P, Csurhes, Peter A, Pfluger, Casey MM, Burrows, Scott R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361480/
https://www.ncbi.nlm.nih.gov/pubmed/24842963
http://dx.doi.org/10.1177/1352458514536252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361480/
https://www.ncbi.nlm.nih.gov/pubmed/24842963
http://dx.doi.org/10.1177/1352458514536252

Ejemplares similares