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Deficiency of CD8(+) effector memory T cells is an early and persistent feature of multiple sclerosis

BACKGROUND: Patients with multiple sclerosis (MS) have a deficiency of circulating CD8(+) T cells, which might impair control of Epstein–Barr virus (EBV) and predispose to MS by allowing EBV-infected autoreactive B cells to accumulate in the central nervous system. Based on the expression of CD45RA...

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Detalles Bibliográficos
Autores principales:	Pender, Michael P, Csurhes, Peter A, Pfluger, Casey MM, Burrows, Scott R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2014
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361480/ https://www.ncbi.nlm.nih.gov/pubmed/24842963 http://dx.doi.org/10.1177/1352458514536252

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