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Catestatin Exerts Direct Protective Effects on Rat Cardiomyocytes Undergoing Ischemia/Reperfusion by Stimulating PI3K-Akt-GSK3β Pathway and Preserving Mitochondrial Membrane Potential

Catestatin (Cst) is a 21-amino acid peptide deriving from Chromogranin A. Cst exerts an overall protective effect against an excessive sympathetic stimulation of cardiovascular system, being able to antagonize catecholamine secretion and to reduce their positive inotropic effect, by stimulating the...

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Detalles Bibliográficos
Autores principales: Bassino, Eleonora, Fornero, Sara, Gallo, Maria Pia, Gallina, Clara, Femminò, Saveria, Levi, Renzo, Tota, Bruno, Alloatti, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361546/
https://www.ncbi.nlm.nih.gov/pubmed/25774921
http://dx.doi.org/10.1371/journal.pone.0119790