Endothelin A Receptor Antagonist, Atrasentan, Attenuates Renal and Cardiac Dysfunction in Dahl Salt-Hypertensive Rats in a Blood Pressure Independent Manner

Proteinuria is a hallmark of chronic kidney disease (CKD) and cardiovascular disease (CVD), and a good predictor of clinical outcome. Selective endothelin A (ET(A)) receptor antagonist used with renin-angiotensin system (RAS) inhibitors prevents development of proteinuria in CKD. However, whether th...

Descripción completa

Detalles Bibliográficos
Autores principales: Samad, Mohammed A., Kim, Ui Kyoung, Kang, Joshua J., Ke, Qingen, Kang, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361570/
https://www.ncbi.nlm.nih.gov/pubmed/25775254
http://dx.doi.org/10.1371/journal.pone.0121664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361570/
https://www.ncbi.nlm.nih.gov/pubmed/25775254
http://dx.doi.org/10.1371/journal.pone.0121664

Ejemplares similares