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Endothelin A Receptor Antagonist, Atrasentan, Attenuates Renal and Cardiac Dysfunction in Dahl Salt-Hypertensive Rats in a Blood Pressure Independent Manner

Proteinuria is a hallmark of chronic kidney disease (CKD) and cardiovascular disease (CVD), and a good predictor of clinical outcome. Selective endothelin A (ET(A)) receptor antagonist used with renin-angiotensin system (RAS) inhibitors prevents development of proteinuria in CKD. However, whether th...

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Detalles Bibliográficos
Autores principales:	Samad, Mohammed A., Kim, Ui Kyoung, Kang, Joshua J., Ke, Qingen, Kang, Peter M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361570/ https://www.ncbi.nlm.nih.gov/pubmed/25775254 http://dx.doi.org/10.1371/journal.pone.0121664

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