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IL-13 Induces YY1 through the AKT Pathway in Lung Fibroblasts

A key feature of lung fibrosis is the accumulation of myofibroblasts. Interleukin 13 (IL-13) is a pro-fibrotic mediator that directly and indirectly influences the activation of myofibroblasts. Transforming growth factor beta (TGF-β) promotes the differentiation of fibroblasts into myofibroblasts, a...

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Detalles Bibliográficos
Autores principales: Guo, Jia, Yao, Hongwei, Lin, Xin, Xu, Haodong, Dean, David, Zhu, Zhou, Liu, Gang, Sime, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361578/
https://www.ncbi.nlm.nih.gov/pubmed/25775215
http://dx.doi.org/10.1371/journal.pone.0119039