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Transforming Growth Factor Beta Signaling Is Essential for the Autonomous Formation of Cartilage-Like Tissue by Expanded Chondrocytes

Cartilage is a tissue with limited self-healing potential. Hence, cartilage defects require surgical attention to prevent or postpone the development of osteoarthritis. For cell-based cartilage repair strategies, in particular autologous chondrocyte implantation, articular chondrocytes are isolated...

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Detalles Bibliográficos
Autores principales: Tekari, Adel, Luginbuehl, Reto, Hofstetter, Willy, Egli, Rainer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361600/
https://www.ncbi.nlm.nih.gov/pubmed/25775021
http://dx.doi.org/10.1371/journal.pone.0120857