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Transforming Growth Factor Beta Signaling Is Essential for the Autonomous Formation of Cartilage-Like Tissue by Expanded Chondrocytes
Cartilage is a tissue with limited self-healing potential. Hence, cartilage defects require surgical attention to prevent or postpone the development of osteoarthritis. For cell-based cartilage repair strategies, in particular autologous chondrocyte implantation, articular chondrocytes are isolated...
Autores principales: | Tekari, Adel, Luginbuehl, Reto, Hofstetter, Willy, Egli, Rainer J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361600/ https://www.ncbi.nlm.nih.gov/pubmed/25775021 http://dx.doi.org/10.1371/journal.pone.0120857 |
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