Fingolimod Prevents Blood-Brain Barrier Disruption Induced by the Sera from Patients with Multiple Sclerosis

OBJECTIVE: Effect of fingolimod in multiple sclerosis (MS) is thought to involve the prevention of lymphocyte egress from lymphoid tissues, thereby reducing autoaggressive lymphocyte infiltration into the central nervous system across blood-brain barrier (BBB). However, brain microvascular endotheli...

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Detalles Bibliográficos
Autores principales: Nishihara, Hideaki, Shimizu, Fumitaka, Sano, Yasuteru, Takeshita, Yukio, Maeda, Toshihiko, Abe, Masaaki, Koga, Michiaki, Kanda, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361641/
https://www.ncbi.nlm.nih.gov/pubmed/25774903
http://dx.doi.org/10.1371/journal.pone.0121488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361641/
https://www.ncbi.nlm.nih.gov/pubmed/25774903
http://dx.doi.org/10.1371/journal.pone.0121488

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