Cargando…

Pregnancy-Induced Amelioration of Muscular Dystrophy Phenotype in mdx Mice via Muscle Membrane Stabilization Effect of Glucocorticoid

Duchenne muscular dystrophy (DMD), the most common and severe type of dystrophinopathy, is an X-linked recessive genetic disease caused by the absence of dystrophin, which leads to fragility and vulnerability of the sarcolemma to mechanical stretching with increased membrane permeability. Currently,...

Descripción completa

Detalles Bibliográficos
Autores principales: Shimizu-Motohashi, Yuko, Asakura, Yoko, Motohashi, Norio, Belur, Nandkishore R., Baumrucker, Michael G., Asakura, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361742/
https://www.ncbi.nlm.nih.gov/pubmed/25775477
http://dx.doi.org/10.1371/journal.pone.0120325