The Glycan Role in the Glycopeptide Immunogenicity Revealed by Atomistic Simulations and Spectroscopic Experiments on the Multiple Sclerosis Biomarker CSF114(Glc)

Glycoproteins are often recognized as not-self molecules by antibodies triggering the onset of severe autoimmune diseases such as Multiple Sclerosis (MS). Thus, the development of antigen-mimicking biomarkers represents an attractive strategy for an early diagnosis of the disease. An example is the...

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Detalles Bibliográficos
Autores principales: Bruno, Agostino, Scrima, Mario, Novellino, Ettore, D'Errico, Gerardino, D'Ursi, Anna Maria, Limongelli, Vittorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361856/
https://www.ncbi.nlm.nih.gov/pubmed/25776265
http://dx.doi.org/10.1038/srep09200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361856/
https://www.ncbi.nlm.nih.gov/pubmed/25776265
http://dx.doi.org/10.1038/srep09200

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