A platform for rapid generation of single and multiplexed reporters in human iPSC lines

Induced pluripotent stem cells (iPSC) are important tools for drug discovery assays and toxicology screens. In this manuscript, we design high efficiency TALEN and ZFN to target two safe harbor sites on chromosome 13 and 19 in a widely available and well-characterized integration-free iPSC line. We...

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Detalles Bibliográficos
Autores principales: Pei, Ying, Sierra, Guadalupe, Sivapatham, Renuka, Swistowski, Andrzej, Rao, Mahendra S., Zeng, Xianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361878/
https://www.ncbi.nlm.nih.gov/pubmed/25777362
http://dx.doi.org/10.1038/srep09205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4361878/
https://www.ncbi.nlm.nih.gov/pubmed/25777362
http://dx.doi.org/10.1038/srep09205

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