TEMPO-derived spin labels linked to the nucleobases adenine and cytosine for probing local structural perturbations in DNA by EPR spectroscopy

Three 2´-deoxynucleosides containing semi-flexible spin labels, namely (T)A, (U)A and (U)C, were prepared and incorporated into deoxyoligonucleotides using the phosphoramidite method. All three nucleosides contain 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) connected to the exocyclic amino group; (...

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Detalles Bibliográficos
Autores principales: Gophane, Dnyaneshwar B, Sigurdsson, Snorri Th
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362019/
https://www.ncbi.nlm.nih.gov/pubmed/25815073
http://dx.doi.org/10.3762/bjoc.11.24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362019/
https://www.ncbi.nlm.nih.gov/pubmed/25815073
http://dx.doi.org/10.3762/bjoc.11.24

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