C-5’-Triazolyl-2’-oxa-3’-aza-4’a-carbanucleosides: Synthesis and biological evaluation

A novel series of 2’-oxa-3’-aza-4’a-carbanucleosides, featured with a triazole linker at the 5’-position, has been developed by exploiting a click chemistry reaction of 5’-azido-2’-oxa-3’-aza-4’a-carbanucleosides with substituted alkynes. Biological tests indicate an antitumor activity for the synth...

Descripción completa

Detalles Bibliográficos
Autores principales: Romeo, Roberto, Carnovale, Caterina, Giofrè, Salvatore V, Chiacchio, Maria A, Garozzo, Adriana, Amata, Emanuele, Romeo, Giovanni, Chiacchio, Ugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362054/
https://www.ncbi.nlm.nih.gov/pubmed/25815087
http://dx.doi.org/10.3762/bjoc.11.38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362054/
https://www.ncbi.nlm.nih.gov/pubmed/25815087
http://dx.doi.org/10.3762/bjoc.11.38

Ejemplares similares