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Dengue vascular leakage is augmented by mast cell degranulation mediated by immunoglobulin Fcγ receptors
Dengue virus (DENV) is the most significant human arboviral pathogen and causes ∼400 million infections in humans each year. In previous work, we observed that mast cells (MC) mediate vascular leakage during DENV infection in mice and that levels of MC activation are correlated with disease severity...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362203/ https://www.ncbi.nlm.nih.gov/pubmed/25783751 http://dx.doi.org/10.7554/eLife.05291 |