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Dengue vascular leakage is augmented by mast cell degranulation mediated by immunoglobulin Fcγ receptors

Dengue virus (DENV) is the most significant human arboviral pathogen and causes ∼400 million infections in humans each year. In previous work, we observed that mast cells (MC) mediate vascular leakage during DENV infection in mice and that levels of MC activation are correlated with disease severity...

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Detalles Bibliográficos
Autores principales:	Syenina, Ayesa, Jagaraj, Cyril J, Aman, Siti AB, Sridharan, Aishwarya, St John, Ashley L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362203/ https://www.ncbi.nlm.nih.gov/pubmed/25783751 http://dx.doi.org/10.7554/eLife.05291

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