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Uni-directional ciliary membrane protein trafficking by a cytoplasmic retrograde IFT motor and ciliary ectosome shedding

The role of the primary cilium in key signaling pathways depends on dynamic regulation of ciliary membrane protein composition, yet we know little about the motors or membrane events that regulate ciliary membrane protein trafficking in existing organelles. Recently, we showed that cilium-generated...

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Detalles Bibliográficos
Autores principales: Cao, Muqing, Ning, Jue, Hernandez-Lara, Carmen I, Belzile, Olivier, Wang, Qian, Dutcher, Susan K, Liu, Yanjie, Snell, William J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362204/
https://www.ncbi.nlm.nih.gov/pubmed/25688564
http://dx.doi.org/10.7554/eLife.05242