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Alteration of synaptic connectivity of oligodendrocyte precursor cells following demyelination

Oligodendrocyte precursor cells (OPCs) are a major source of remyelinating oligodendrocytes in demyelinating diseases such as Multiple Sclerosis (MS). While OPCs are innervated by unmyelinated axons in the normal brain, the fate of such synaptic contacts after demyelination is still unclear. By comb...

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Detalles Bibliográficos
Autores principales: Sahel, Aurélia, Ortiz, Fernando C., Kerninon, Christophe, Maldonado, Paloma P., Angulo, María Cecilia, Nait-Oumesmar, Brahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362325/
https://www.ncbi.nlm.nih.gov/pubmed/25852473
http://dx.doi.org/10.3389/fncel.2015.00077