DNA polymerase γ and disease: what we have learned from yeast

Mip1 is the Saccharomyces cerevisiae DNA polymerase γ (Pol γ), which is responsible for the replication of mitochondrial DNA (mtDNA). It belongs to the family A of the DNA polymerases and it is orthologs to human POLGA. In humans, mutations in POLG(1) cause many mitochondrial pathologies, such as pr...

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Detalles Bibliográficos
Autores principales: Lodi, Tiziana, Dallabona, Cristina, Nolli, Cecilia, Goffrini, Paola, Donnini, Claudia, Baruffini, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362329/
https://www.ncbi.nlm.nih.gov/pubmed/25852747
http://dx.doi.org/10.3389/fgene.2015.00106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362329/
https://www.ncbi.nlm.nih.gov/pubmed/25852747
http://dx.doi.org/10.3389/fgene.2015.00106

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