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Kidney-specific expression of GFP by in-utero delivery of pseudotyped adeno-associated virus 9

Gene therapy targeting of kidneys has been largely unsuccessful. Recently, a recombinant adeno-associated virus (rAAV) vector was used to target adult mouse kidneys. Our hypothesis is that a pseudotyped rAAV 2/9 vector can produce fetal kidney-specific expression of the green fluorescent protein (GF...

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Detalles Bibliográficos
Autores principales: Picconi, Jason L, Muff-Luett, Melissa A, Wu, Di, Bunchman, Erik, Schaefer, Franz, Brophy, Patrick D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362350/
https://www.ncbi.nlm.nih.gov/pubmed/26015958
http://dx.doi.org/10.1038/mtm.2014.14