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Kidney-specific expression of GFP by in-utero delivery of pseudotyped adeno-associated virus 9
Gene therapy targeting of kidneys has been largely unsuccessful. Recently, a recombinant adeno-associated virus (rAAV) vector was used to target adult mouse kidneys. Our hypothesis is that a pseudotyped rAAV 2/9 vector can produce fetal kidney-specific expression of the green fluorescent protein (GF...
Autores principales: | Picconi, Jason L, Muff-Luett, Melissa A, Wu, Di, Bunchman, Erik, Schaefer, Franz, Brophy, Patrick D |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362350/ https://www.ncbi.nlm.nih.gov/pubmed/26015958 http://dx.doi.org/10.1038/mtm.2014.14 |
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