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Recombinant rabies virus particles presenting botulinum neurotoxin antigens elicit a protective humoral response in vivo

Botulinum neurotoxins are one of the most potent toxins found in nature, with broad medical applications from cosmetics to the treatment of various neuropathies. Additionally, these toxins are classified as Category A-Tier 1 agents, with human lethal doses calculated at as little as 90 ng depending...

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Detalles Bibliográficos
Autores principales: Hudacek, Andrew W, Al-Saleem, Fetweh H, Willet, Mallory, Eisemann, Travis, Mattis, Jeffrey A, Simpson, Lance L, Schnell, Matthias J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362357/
https://www.ncbi.nlm.nih.gov/pubmed/26015984
http://dx.doi.org/10.1038/mtm.2014.46