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EC4, a truncation of soluble N-cadherin, reduces vascular smooth muscle cell apoptosis and markers of atherosclerotic plaque instability

Atherosclerotic plaque instability is precipitated by vascular smooth muscle cell apoptosis in the fibrous cap, weakening it and leading to plaque rupture. We previously showed that reducing smooth muscle cell apoptosis with soluble N-cadherin (SNC) increased features of plaque stability. We have no...

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Detalles Bibliográficos
Autores principales: Lyon, Cressida A, Johnson, Jason L, White, Stephen, Sala-Newby, Graciela B, George, Sarah J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362368/
https://www.ncbi.nlm.nih.gov/pubmed/26015951
http://dx.doi.org/10.1038/mtm.2014.4