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EC4, a truncation of soluble N-cadherin, reduces vascular smooth muscle cell apoptosis and markers of atherosclerotic plaque instability
Atherosclerotic plaque instability is precipitated by vascular smooth muscle cell apoptosis in the fibrous cap, weakening it and leading to plaque rupture. We previously showed that reducing smooth muscle cell apoptosis with soluble N-cadherin (SNC) increased features of plaque stability. We have no...
Autores principales: | Lyon, Cressida A, Johnson, Jason L, White, Stephen, Sala-Newby, Graciela B, George, Sarah J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362368/ https://www.ncbi.nlm.nih.gov/pubmed/26015951 http://dx.doi.org/10.1038/mtm.2014.4 |
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