Developmental stage determines efficiency of gene transfer to muscle satellite cells by in utero delivery of adeno-associated virus vector serotype 2/9

Efficient gene transfer to muscle stem cells (satellite cells) has not been achieved despite broad transduction of skeletal muscle by systemically administered adeno-associated virus serotype 2/9 (AAV-9) in mice. We hypothesized that cellular migration during fetal development would make satellite c...

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Detalles Bibliográficos
Autores principales: Stitelman, David H, Brazelton, Tim, Bora, Archana, Traas, Jeremy, Merianos, Demetri, Limberis, Maria, Davey, Marcus, Flake, Alan W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362369/
https://www.ncbi.nlm.nih.gov/pubmed/26015979
http://dx.doi.org/10.1038/mtm.2014.40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362369/
https://www.ncbi.nlm.nih.gov/pubmed/26015979
http://dx.doi.org/10.1038/mtm.2014.40

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