Quantitative, noninvasive, in vivo longitudinal monitoring of gene expression in the brain by co-AAV transduction with a PET reporter gene

In vivo imaging of vector transgene expression would be particularly valuable for repetitive monitoring of therapy in the brain, where invasive tissue sampling is contraindicated. We evaluated adeno-associated virus vector expression of a dopamine-2 receptor (D2R) mutant (D2R80A) by positron emissio...

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Detalles Bibliográficos
Autores principales: Yoon, Sea Young, Gay-Antaki, Carlos, Ponde, Datta E, Poptani, Harish, Vite, Charles H, Wolfe, John H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362377/
https://www.ncbi.nlm.nih.gov/pubmed/26015960
http://dx.doi.org/10.1038/mtm.2014.16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362377/
https://www.ncbi.nlm.nih.gov/pubmed/26015960
http://dx.doi.org/10.1038/mtm.2014.16

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