Pre-TCRα supports CD3-dependent reactivation and expansion of TCRα-deficient primary human T-cells

Chimeric antigen receptor technology offers a highly effective means for increasing the anti-tumor effects of autologous adoptive T-cell immunotherapy, and could be made widely available if adapted to the use of allogeneic T-cells. Although gene-editing technology can be used to remove the alloreact...

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Detalles Bibliográficos
Autores principales: Galetto, Román, Lebuhotel, Celine, Poirot, Laurent, Gouble, Agnès, Toribio, Maria L, Smith, Julianne, Scharenberg, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362381/
https://www.ncbi.nlm.nih.gov/pubmed/26015965
http://dx.doi.org/10.1038/mtm.2014.21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362381/
https://www.ncbi.nlm.nih.gov/pubmed/26015965
http://dx.doi.org/10.1038/mtm.2014.21

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